Cobalt toxicity — an emerging clinical problem in patients with metal‐on‐metal hip prostheses?

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منابع مشابه

Cobalt and chromium measurement in patients with metal hip prostheses.

Approximately 1 million metal-on-metal (MoM) hip prostheses have been implanted worldwide to alleviate pain, restore hip function, and improve overall quality of life. These implants contain femoral and acetabular bearing surfaces that are typically composed predominantly of cobalt (Co) and chromium (Cr). Although the majority of MoM hip replacements have been successful, multiple recent report...

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Metal release from hip prostheses: cobalt and chromium toxicity and the role of the clinical laboratory.

Individuals with advanced hip disease suffer from pain, impaired hip function, and decreased quality of life. Roughly one million metal-on-metal (MoM) hip prostheses have been implanted worldwide in order to ameliorate these issues. While most MoM hip replacements are successful, some patients suffer from serious adverse effects secondary to the release of metal debris due to implant wear and c...

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Clinical Outcomes of Total Hip Arthroplasty in Patients with Ankylosed Hip

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Cobalt Cardiomyopathy Secondary to Hip Arthroplasty: An Increasingly Prevalent Problem

A forty-year-old man experienced worsening heart failure four years following bilateral complicated total hip replacement. His condition was extensively worked up but no underlying pathology was immediately evident. Given the cobalt-chromium alloy component present in the hip arthroplasties, the raised cobalt blood levels, and a fitting clinical picture coupled with radiological findings, the p...

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Blood nickel concentrations in patients with stainless-steel hip prostheses.

Nickel concentrations were analyzed by electrothermal atomic absorption spectrophotometry in serum and whole blood specimens from patients 9 to 15 years after unilateral (N = 11) or bilateral (N = 2) hip arthroplasty. The hip prostheses were of the "Charnley" or "TR-28" (metal-to-plastic) types, fabricated of stainless-steel (14 to 16 percent Ni) with polyethylene acetabular cups. In 12 of the ...

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ژورنال

عنوان ژورنال: Medical Journal of Australia

سال: 2011

ISSN: 0025-729X,1326-5377

DOI: 10.5694/j.1326-5377.2011.tb03151.x